Mouse Resistance Against Foot-and-Mouth Disease Virus Induced by Injections of Pyran-Reference-Cited by-同舟云学术

Mouse Resistance Against Foot-and-Mouth Disease Virus Induced by Injections of Pyran

Published:1971-02 Issue:2 Volume:3 Page:249-253
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Richmond Jonathan Y.¹

Affiliation:

1. Plum Island Animal Disease Laboratory, Veterinary Sciences Research Division, Agricultural Research Service, U.S. Department of Agriculture, Greenport, New York 11944

Abstract

Mouse resistance to foot-and-mouth disease virus (FMDV) was induced by intraperitoneal injections of pyran copolymer. A biphasic pattern of protection occurred with greatest resistance 4 and 48 hr after injection of this polyanion. Viremia was not detectable in pretreated mice challenge-exposed with FMDV. Incubation of virus with pyran did not alter viral infectivity in mice or tissue culture. Serum interferon was demonstrated 1 and 2 days after pyran administration.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.3.2.249-253.1971

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