Hybrid Vigor: Importance of Hybrid λ Phages in Early Insights in Molecular Biology-Reference-Cited by-同舟云学术

Hybrid Vigor: Importance of Hybrid λ Phages in Early Insights in Molecular Biology

Published:2022-12-21 Issue:4 Volume:86 Page:
ISSN:1092-2172
Container-title:Microbiology and Molecular Biology Reviews
language:en
Short-container-title:Microbiol Mol Biol Rev

Author:

Feiss Michael¹^ORCID,Young Ryland²³,Ramsey Jolene²³^ORCID,Adhya Sankar⁴,Georgopoulos Costa⁵,Hendrix Roger W.⁶⁷,Hatfull Graham F.⁶⁷^ORCID,Gilcrease Eddie B.⁸,Casjens Sherwood R.⁹¹⁰^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA

2. Center for Phage Technology, Texas A&M AgriLife Research, College Station, Texas, USA

3. Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA

4. Laboratory of Molecular Biology, Center for Cancer Research, The National Cancer Institute, Bethesda, Maryland, USA

5. Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, USA

6. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

7. Pittsburgh Bacteriophage Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

8. Department of Civil and Environmental Engineering, University of Utah, Salt Lake City, Utah, USA

9. Division of Microbiology and Immunology, Pathology Department, University of Utah School of Medicine, Salt Lake City, Utah, USA

10. School of Biological Sciences, University of Utah, Salt Lake City, Utah, USA

Abstract

Laboratory-generated hybrids between phage λ and related phages played a seminal role in establishment of the λ model system, which, in turn, served to develop many of the foundational concepts of molecular biology, including gene structure and control. Important λ hybrids with phages 21 and 434 were the earliest of such phages. To understand the biology of these hybrids in full detail, we determined the complete genome sequences of phages 21 and 434.

Funder

National Institutes of Health

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Link

https://journals.asm.org/doi/pdf/10.1128/mmbr.00124-21

Reference192 articles.

1. Lysogenicity in Escherichia coli strain K-12;Lederberg EM;Microb Genet Bull,1950

2. Strains of phage lambda in current use

3. A genetic study of the temperate coliphage λ

4. Bacteriophage λ PaPa : Not the Mother of All λ Phages

5. Jacob F, Wollman EL. 1961. Sexuality and the genetics of bacteria. Academic Press, New York, NY.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Research on phage λ: a lucky choice;EcoSal Plus;2023-12-22