The CD8 + T Cell Noncytotoxic Antiviral Responses-Reference-Cited by-同舟云学术

The CD8 + T Cell Noncytotoxic Antiviral Responses

Published:2021-05-19 Issue:2 Volume:85 Page:
ISSN:1092-2172
Container-title:Microbiology and Molecular Biology Reviews
language:en
Short-container-title:Microbiol Mol Biol Rev

Author:

Morvan Maelig G.¹^ORCID,Teque Fernando C.¹,Locher Christopher P.²,Levy Jay A.¹^ORCID

Affiliation:

1. Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA

2. Versatope Therapeutics Inc., Lowell, Massachusetts, USA

Abstract

The CD8 + T cell noncytotoxic antiviral response (CNAR) was discovered during studies of asymptomatic HIV-infected subjects more than 30 years ago. In contrast to CD8 + T cell cytotoxic lymphocyte (CTL) activity, CNAR suppresses HIV replication without target cell killing.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Link

https://journals.asm.org/doi/pdf/10.1128/MMBR.00155-20

Reference435 articles.

1. Predicting the Impact of CD8+ T Cell Polyfunctionality on HIV Disease Progression

2. CD8 + Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

3. The Binding and Lysis of Target Cells by Cytotoxic Lymphocytes: Molecular and Cellular Aspects

4. Regulation of CD8+ T-cell cytotoxicity in HIV-1 infection

5. Antigenic Restimulation of Virus-Specific Memory CD8 + T Cells Requires Days of Lytic Protein Accumulation for Maximal Cytotoxic Capacity

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