p53 Ubiquitination Comediated by HUWE1 and TRAF6 Contributes to White Spot Syndrome Virus Infection in Crustacean-Reference-Cited by-同舟云学术

p53 Ubiquitination Comediated by HUWE1 and TRAF6 Contributes to White Spot Syndrome Virus Infection in Crustacean

Published:2022-03-23 Issue:6 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Gong Yi¹²³⁴,Kong Tongtong¹³,Aweya Jude Juventus¹²³⁴^ORCID,Ma Hongyu¹²³⁴,Zhang Yueling¹²³⁴,Li Shengkang¹²³⁴^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Marine Biology, Shantou University, Shantou, China

2. Southern Marine Science and Engineering Guangdong Laboratory, Guangzhou, China

3. Institute of Marine Sciences, Shantou University, Shantou, China

4. STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, China

Abstract

p53, which is a well-known tumor suppressor that has been widely studied in higher animals, has been reported to be tightly controlled at low levels by ubiquitin-dependent proteasomal degradation. However, recent p53 ubiquitination-relevant research mainly involved an individual E3 ubiquitin ligase, but not whether there exist other mechanisms that need to be explored.

Funder

2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.02029-21

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