A growth factor-responsive gene of murine BALB/c 3T3 cells encodes a protein homologous to human tissue factor-Reference-Cited by-同舟云学术

A growth factor-responsive gene of murine BALB/c 3T3 cells encodes a protein homologous to human tissue factor

Published:1989-06 Issue:6 Volume:9 Page:2567-2573
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Hartzell S¹,Ryder K¹,Lanahan A¹,Lau L F¹,Nathan D¹

Affiliation:

1. Howard Hughes Medical Institute Laboratory, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Abstract

Polypeptide growth factors rapidly induce the transcription of a set of genes that appear to mediate cell growth. We report that one of the genes induced in BALB/c mouse 3T3 cells encodes a transmembrane protein (mTF) homologous to human tissue factor, which is involved in the proteolytic activation of blood clotting. mTF mRNA is present in many murine tissues and cell lines. Our results raise the possibility that mTF may also play a role in cell growth.

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/mcb.9.6.2567-2573.1989

Reference38 articles.

1. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators;Caput D.;Proc. Natl. Acad. Sci. USA,1986

2. A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells;Chavrier P.;EMBO J.,1988

3. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger' sequences;Christy B.;Proc. Natl. Acad. Sci. USA,1988

4. Molecular cloning of gene sequences regulated by platelet-derived growth factor;Cochran B. H.;Cell,1983

5. 46 Kd mannose-6-phosphate receptor: cloning, expression, and homology to the 215 kd mannose-6-phosphate receptor;Dahms N. M.;Cell,1987

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