MICs of Oxazolidinones for Rhodococcus equi Strains Isolated from Humans and Animals

Author:

Bowersock Terry L.1,Salmon Sarah A.1,Portis Ellen S.1,Prescott John F.2,Robison Denise A.3,Ford Charles W.4,Watts Jeffrey L.1

Affiliation:

1. Animal Health Therapeutics Research,1 and

2. Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G 2W12; and

3. University Hospitals, Oklahoma City, Oklahoma 731263

4. Infectious Diseases Research,4 Pharmacia & Upjohn, Kalamazoo, Michigan 49001;

Abstract

ABSTRACT Eperezolid and linezolid are representatives of a new class of orally active, synthetic antimicrobial agents. The in vitro activity values (MICs) of linezolid, eperezolid, and comparator antibiotics against 102 strains of Rhodococcus equi isolated from humans and animals were determined. Linezolid was more active than eperezolid against the strains tested; premafloxacin was the most active comparator antibiotic.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference15 articles.

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