Multicenter Surveillance of Antimicrobial Resistance of Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis in Taiwan during the 1998–1999 Respiratory Season

Author:

Hsueh Po-Ren1,Liu Yung-Ching2,Shyr Jainn-Ming3,Wu Tsu-Lan4,Yan Jing-Jou5,Wu Jiunn-Jong5,Leu Hsieh-Shong4,Chuang Yin-Ching5,Yeu-Jen Lau 3,Luh Kwen-Tay1

Affiliation:

1. Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, Taipei,1

2. Veterans General Hospital, Kaohsiung,2

3. Veterans General Hospital, Taichung,3

4. Chang Gung Memorial Hospital, LinKou,4 and

5. National Cheng-Kung University Hospital, Tainan,5 Taiwan

Abstract

ABSTRACT A susceptibility surveillance study of 276 isolates of Streptococcus pneumoniae , 301 of Haemophilus influenzae , and 110 of Moraxella catarrhalis was carried out from November 1998 to May 1999 in Taiwan. High rates of nonsusceptibility to penicillin (76%), extended-spectrum cephalosporins (56%), azithromycin (94%), clarithromycin (95%), and trimethoprim-sulfamethoxazole (TMP-SMX) (65%) for S. pneumoniae isolates and high rates of nonsusceptibility to amoxicillin (58%) and TMP-SMX (52%) for H. influenzae isolates were found. Higher percentages of S. pneumoniae isolates nonsusceptible to aminopenicillins, extended-spectrum cephalosporins, macrolides, and TMP-SMX were observed among penicillin-intermediate and -resistant isolates. All quinolones tested were active in vitro against these three organisms.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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