Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1-Reference-Cited by-同舟云学术

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

Published:2008-04 Issue:4 Volume:46 Page:1530-1533
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Åkerlund Thomas¹,Persson Ingela¹,Unemo Magnus²,Norén Torbjörn³,Svenungsson Bo⁴,Wullt Marlene⁵,Burman Lars G.¹

Affiliation:

1. Department of Bacteriology, Swedish Institute for Infectious Disease Control, Solna, Sweden

2. Department of Clinical Microbiology

3. Department of Infectious Diseases, Örebro University Hospital, Örebro, Sweden

4. Department of Communicable Disease Control and Prevention, Karolinska University Hospital, Stockholm, Sweden

5. Department of Clinical Sciences, Infectious Disease Research Unit, Malmö University Hospital, Lund University, Malmö, Sweden

Abstract

ABSTRACT Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01964-07

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