Abstract
Studies were made on the growth of Mycobacterium lepraemurium in cultures of macrophages obtained from various sources, such as bone marrow, spleen, and blood of mice. Macrophages were maintained in good condition for more than 12 weeks. Marked intracellular multiplication of M. lepraemurium was observed in cultures from all three sources. Whereas M. lepraemurium freshly prepared from the animals showed good growth in the cultures, those that were kept at 4 degrees C for 10 or 14 days showed no growth.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference7 articles.
1. Growth of macrophages obtained from various sources;Chang Y. T.;Int. J. Lepr.,1976
2. Chang Y. T. R. N. Andersen and Z. Vaituzis. 1967. Growth of Mycobacterium lepraemurium in cultures of mouse peritoneal macrophages. 93:1119-1131. J. Bacteriol.
3. Incorporation of tritiated thymidine by leprosy bacilli in cultures of human lepromatous macrophages;Drutz D. J.;J. Infect. Dis.,1972
4. A guide to the counting of mycobacteria in clinical and experimental materials;Hanks J. H.;Int. J. Lepr.,1964
5. A31 cell as a host of Mycobacterium lepraemurium and Mycobacterium leprae;Ito T.;Int. J. Lepr.,1976
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献