A Genomic Day in the Life of a Clinical Microbiology Laboratory

Author:

Long S. Wesley12,Williams Dawn1,Valson Chandni12,Cantu Concepcion C.12,Cernoch Patricia1,Musser James M.12,Olsen Randall J.12

Affiliation:

1. Department of Pathology and Genomic Medicine, The Methodist Hospital

2. Center for Molecular and Translational Human Infectious Disease Research, The Methodist Hospital Research Institute, Houston, Texas, USA

Abstract

ABSTRACT Next-generation sequencing technology is available to many clinical laboratories; however, it is not yet widely used in routine microbiology practice. To demonstrate the feasibility of using whole-genome sequencing in a routine clinical microbiology workflow, we sequenced the genome of every organism isolated in our laboratory for 1 day.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference11 articles.

1. Bacterial genomics in infectious disease and the clinical pathology laboratory;Olsen RJ;Arch. Pathol. Lab. Med,2012

2. Microbial Genomics and Infectious Diseases

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4. Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts;D'Souza CA;mBio,2011

5. Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients

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