Enterovirus-Cardiomyocyte Interactions: Impact of Terminally Deleted Genomic RNAs on Viral and Host Functions-Reference-Cited by-同舟云学术

Enterovirus-Cardiomyocyte Interactions: Impact of Terminally Deleted Genomic RNAs on Viral and Host Functions

Published:2023-01-31 Issue:1 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Bouin Alexis¹,Vu Michelle N.¹,Al-Hakeem Ali¹,Tran Genevieve P.¹,Nguyen Joseph H. C.¹,Semler Bert L.¹^ORCID

Affiliation:

1. Department of Microbiology & Molecular Genetics, School of Medicine and Center for Virus Research, University of California, Irvine, California, USA

Abstract

Enteroviruses like coxsackievirus B3 are able to initiate acute infections of cardiac tissue and, in some cases, to establish a long-term persistent infection that can lead to serious disease sequelae, including dilated cardiomyopathy. Previous studies have demonstrated the presence of 5′ terminally deleted forms of enterovirus RNAs in heart tissues derived from patients with dilated cardiomyopathy.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01426-22

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