Increasing Importance of Balamuthia mandrillaris-Reference-Cited by-同舟云学术

Increasing Importance of Balamuthia mandrillaris

Published:2008-07 Issue:3 Volume:21 Page:435-448
ISSN:0893-8512
Container-title:Clinical Microbiology Reviews
language:en
Short-container-title:Clin Microbiol Rev

Author:

Matin Abdul¹,Siddiqui Ruqaiyyah¹,Jayasekera Samantha¹,Khan Naveed Ahmed¹

Affiliation:

1. School of Biological and Chemical Sciences, Birkbeck, University of London, London, England

Abstract

SUMMARY Balamuthia mandrillaris is an emerging protozoan parasite, an agent of granulomatous amoebic encephalitis involving the central nervous system, with a case fatality rate of >98%. This review presents our current understanding of Balamuthia infections, their pathogenesis and pathophysiology, and molecular mechanisms associated with the disease, as well as virulence traits of Balamuthia that may be potential targets for therapeutic interventions and/or for the development of preventative measures.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Link

https://journals.asm.org/doi/pdf/10.1128/CMR.00056-07

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