Genome Sequences of Novel Torque Teno Viruses Identified in Human Brain Tissue

Author:

Kraberger Simona1,Mastroeni Diego23,Delvaux Elaine2,Varsani Arvind1345ORCID

Affiliation:

1. The Biodesign Center for Fundamental and Applied Microbiomics, School of Life Sciences, Arizona State University, Tempe, Arizona, USA

2. The Biodesign ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA

3. School of Life Sciences, Arizona State University, Tempe, Arizona, USA

4. Center for Evolution and Medicine, Arizona State University, Tempe, Arizona, USA

5. Structural Biology Research Unit, Department of Clinical Laboratory Sciences, University of Cape Town Observatory, Cape Town, South Africa

Abstract

Complete genome sequences of two novel torque teno viruses (TTVs) were identified in human brain tissue. These sequences are 3,245 nucleotides (nt) and 2,900 nt long and share 68% and 72% open reading frame 1 (ORF1) identity, respectively, with other human TTVs. This report extends the identification of TTV sequences in the brain.

Funder

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | National Institute on Aging

ADHS | Arizona Biomedical Research Commission

Arizona Department of Health Services

Michael J. Fox Foundation for Parkinson's Research

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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