Early Detection of Hepatitis C Virus Infection by Use of a New Combined Antigen-Antibody Detection Assay: Potential Use for High-Risk Individuals-Reference-Cited by-同舟云学术

Early Detection of Hepatitis C Virus Infection by Use of a New Combined Antigen-Antibody Detection Assay: Potential Use for High-Risk Individuals

Published:2006-04 Issue:4 Volume:44 Page:1561-1563
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Schnuriger A.¹,Dominguez S.²,Valantin M.-A.²,Tubiana R.²,Duvivier C.²,Ghosn J.²,Simon A.³,Katlama C.²,Thibault V.¹

Affiliation:

1. Virology

2. Infectious Diseases

3. Internal Medicine Departments, Pitié-Salpêtrière Hospital, Paris, France

Abstract

ABSTRACT The performance of a new combined antigen-antibody assay (Monolisa HCV Ag-Ab Ultra; Bio-Rad Laboratories) was evaluated in the context of acute hepatitis C in human immunodeficiency virus-infected patients. The combined assay became positive as early as the first PCR and earlier than a third-generation enzyme-linked immunosorbent assay in 65% of the cases. Reduction of the long period of HCV seronegativity should improve the diagnosis of hepatitis C infection, especially in high-risk populations.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.44.4.1561-1563.2006

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