Nalidixic Acid-Induced Protein Alterations in Escherichia coli-Reference-Cited by-同舟云学术

Nalidixic Acid-Induced Protein Alterations in Escherichia coli

Published:1977-01 Issue:1 Volume:11 Page:167-170
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chao Lee¹

Affiliation:

1. Department of Biochemistry, Medical University of South Carolina, Charleston, South Carolina 29401

Abstract

The effect of nalidixic acid on pulse-labeled protein patterns was analyzed by sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis. The drug was found to alter protein patterns in a drug-sensitive strain but not in the isogenic drug-resistant strain of Escherichia coli . The drug-induced alteration of protein patterns was demonstrated by the appearance of some and the disappearance of other pulse-labeled peptides elicited by the drug.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.11.1.167

Reference24 articles.

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