Comparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae

Author:

Jorgensen J H,Redding J S,Howell A W

Abstract

LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference12 articles.

1. Susceptibility studies of multiply resistant Haemophilus influenzae isolated from pediatric patients and contacts;Campos J.;Antimicrob. Agents Chemother.,1984

2. Comparison of ceftriaxone and traditional therapy of bacterial meningitis;Congeni B. L.;Antimicrob. Agents Chemother.,1984

3. Hansman D. 1975. Haemophilus influenzae type b resistant to tetracycline. Lancet i:893-896.

4. Antimicrobial resistance of Haemophilus species in patients with chronic bronchitis;Kauffman C. A.;Am. Rev. Respir. Dis.,1979

5. Meningitis due to Haemophilus influenzae type b resistant to both ampicillin and chloramphenicol;Kenny J. F.;Pediatrics,1980

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