Oral ribavirin treatment of influenza A and B

Author:

Stein D S,Creticos C M,Jackson G G,Bernstein J M,Hayden F G,Schiff G M,Bernstein D I

Abstract

A loading dose and short-term administration of oral ribavirin significantly improved symptoms and signs of influenza type A or B infection in 25 patients. The antiviral effect was not significant. No adverse clinical effects or significant laboratory values were observed. Oral treatment of patients with influenza A or B infection might be possible with ribavirin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference13 articles.

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4. Knight V. S. Z. Wilson J. M. Quarles S. E. Greggs H. W. McClung B. K. Waters R. W. Cameron J. M. Zerwas and R. B. Couch. 1981. Ribavirin small particle aerosol treatment of influenza. Lancet i:945-949.

5. Double-blind evaluation of oral ribavirin (Virazole) in experimental influenza A virus infection in volunteers;Magnussen C. R.;Antimicrob. Agents Chemother.,1977

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