Natural History of Intestinal Microsporidiosis among Patients Infected with Human Immunodeficiency Virus

Author:

Dascomb Kristin1,Clark Rebecca1,Aberg Judith2,Pulvirenti Joseph3,Hewitt Ross G.4,Kissinger Patricia1,Didier Elizabeth S.5

Affiliation:

1. LSU School of Medicine, Tulane School of Public Health and Tropical Medicine, New Orleans,1 and

2. San Francisco General Hospital, San Francisco, California2;

3. Cook County Hospital, Chicago, Illinois3; and

4. State University of New York, Buffalo, New York4

5. Tulane Regional Primate Center, Covington,5 Louisiana;

Abstract

ABSTRACT A chart review of 73 human immunodeficiency virus (HIV)-infected patients with enteric microsporidiosis was conducted to define the natural history of microsporidiosis. A substantial proportion of patients remained symptomatic after 6 months (54.8% with persistent diarrhea and 51.2% with weight loss). Predictors for persistent diarrhea included high HIV RNA viral load and no initiation of protease inhibitor therapy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference7 articles.

1. Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy;Carr A.;Lancet,1998

2. Quantitative light microscopic detection of Enterocytozoon bieneusi in stool specimens: a longitudinal study of human immunodeficiency virus-infected microsporidiosis patients

3. Comparison of three staining methods for detecting microsporidia in fluids

4. Remission of AIDS-associated intestinal microsporidiosis with highly active antiretroviral therapy;Goguel J.;AIDS,1997

5. Pitie-Salpetriere G. H. Effects of triple antiretroviral therapies including a HIV protease inhibitor on chronic intestinal cryptosporidiosis and microsporidiosis in HIV-infected patients abstr. 357.Proceedings of the Fourth Conference on Retrovirology and Opportunistic Infections1997

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