Affiliation:
1. Columbia Hospital, Milwaukee, Wisconsin 53211
Abstract
Hemolytic
Haemophilus
are rarely isolated in the clinical laboratory, as they do not grow on sheep or human blood-agar alone. On rabbit blood-agar they grow well and are hemolytic, but they grow less well and are not hemolytic on sheep blood-agar with added X and V factors. A survey was made to determine their incidence in pharyngitis. From 28 of 100 sore throats and from 57 of 100 normal throats, only normal bacterial flora were isolated. β-Streptococci were present in significant numbers in 9 sore and 11 normal throats; staphylococci in 8 sore and 4 normal throats; pneumococci in 20 sore and 11 normal throats;
H. influenzae
or
H. parainfluenzae
in 13 sore and no normal throats; hemolytic
Haemophilus
in 30 sore and 18 normal throats; enteric bacilli in 1 of each;
Candida
and
Neisseria
in 2 sore throats each. All of the 33 hemolytic
Haemophilus
isolates identified to species were
H. parahaemolyticus
. All were sensitive in vitro to chloramphenicol, erythromycin, and tetracycline; 30 were sensitive to ampicillin and 30 to penicillin, 26 to novobiocin, and 12 to methicillin.
H. influenzae, H. parainfluenzae
, and
H. haemolyticus
are indistinguishable by Gram stain morphology, but
H. parahaemolyticus
is larger than the other three. Hemolytic and nonhemolytic species are indistinguishable by colonial morphology or by nutritional requirements; only hemolysis gives positive differentiation. Nevertheless, only rarely would this be of clinical importance.
H. parahaemolyticus
apparently may cause pharyngitis, but it is almost always susceptible to penicillin and rarely if ever causes sequelae.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
4 articles.
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