Watching DNA Replication Inhibitors in Action: Exploiting Time-Lapse Microfluidic Microscopy as a Tool for Target-Drug Interaction Studies in Mycobacterium-Reference-Cited by-同舟云学术

Watching DNA Replication Inhibitors in Action: Exploiting Time-Lapse Microfluidic Microscopy as a Tool for Target-Drug Interaction Studies in Mycobacterium

Published:2019-10 Issue:10 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Trojanowski Damian¹,Kołodziej Marta¹,Hołówka Joanna¹,Müller Rolf²³,Zakrzewska-Czerwińska Jolanta¹

Affiliation:

1. Faculty of Biotechnology, Department of Molecular Microbiology, University of Wroclaw, Wroclaw, Poland

2. German Centre for Infection Research (DZIF), Hannover, Hannover-Braunschweig, Germany

3. Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research and Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken, Germany

Abstract

Spreading resistance to antibiotics and the emergence of multidrug-resistant strains have become frequent in many bacterial species, including mycobacteria, which are the causative agents of severe diseases and which have profound impacts on global health.

Funder

Narodowe Centrum Nauki

MNiSW | Krajowy Naukowy Osrodek Wiodacy

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00739-19

Reference76 articles.

1. Fix the antibiotics pipeline

2. The global threat of antimicrobial resistance: science for intervention