Energy Metabolism of Bloodstream Form Trypanosoma theileri-Reference-Cited by-同舟云学术

Energy Metabolism of Bloodstream Form Trypanosoma theileri

Published:2007-09 Issue:9 Volume:6 Page:1693-1696
ISSN:1535-9778
Container-title:Eukaryotic Cell
language:en
Short-container-title:Eukaryot Cell

Author:

van Hellemond Jaap J.¹²,Hoek Aad³,Schreur Paul Wichgers¹,Chupin Vladimir⁴,Özdirekcan Suat⁴,Geysen Dirk⁵,van Grinsven Koen W. A.¹,Koets Ad P.⁶,Van den Bossche Peter⁵,Geerts Stanny⁵,Tielens Aloysius G. M.¹²

Affiliation:

1. Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, 3584 CM Utrecht, The Netherlands

2. Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

3. Division of Immunology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands

4. Department of Biochemistry of Membranes, Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CH Utrecht, The Netherlands

5. Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerpen, Belgium

6. Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands

Abstract

ABSTRACT Bloodstream form Trypanosoma theileri degrades glucose to acetate (47%) and succinate (45%) and, therefore, does not solely rely on glycolysis for ATP production. This trypanosomatid does not use amino acids for energy metabolism. These results refute the prevailing hypothesis that substrate availability determines the type of energy metabolism of trypanosomatids.

Publisher

American Society for Microbiology

Subject

Molecular Biology,General Medicine,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/EC.00130-07

Reference21 articles.

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