Genetically Engineered Wine Yeast Produces a High Concentration of l -Lactic Acid of Extremely High Optical Purity-Reference-Cited by-同舟云学术

Genetically Engineered Wine Yeast Produces a High Concentration of l -Lactic Acid of Extremely High Optical Purity

Published:2005-05 Issue:5 Volume:71 Page:2789-2792
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Saitoh Satoshi¹,Ishida Nobuhiro²,Onishi Toru¹,Tokuhiro Kenro²,Nagamori Eiji²,Kitamoto Katsuhiko³,Takahashi Haruo²

Affiliation:

1. Toyota Biotechnology & Afforestation Laboratory, Toyota Motor Co., Miyoshi-cho, Aichi 470-0201

2. Biotechnology Laboratory, Toyota Central R&D Labs, Inc., Nagakute-cho, Aichi 480-1192

3. Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan

Abstract

ABSTRACT For mass production of lactic acid, we newly constructed a transgenic wine yeast strain that included six copies of the bovine l -lactate dehydrogenase gene on the genome. On fermentation in inexpensive cane juice-based medium, l -lactate production of this recombinant reached 122 g/liter and the optical purity was 99.9% or higher.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.71.5.2789-2792.2005

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