Antibacterial Effect of Cysteine-Nitrosothiol and Possible Percursors Thereof

Author:

Incze K.123,Farkas J.123,Mihályi Vilma123,Zukál E.123

Affiliation:

1. Hungarian Meat Research Institute, H-1097, Budapest, Hungary

2. Central Food Research Institute, H-1022, Budapest, Hungary

3. Central Institute for Quality Control and Analysis of Food, H-1052 Budapest, Hungary

Abstract

The postulated intermediate of nitrite-myoglobin reaction, cysteine-nitrosothiol, was prepared and its antibacterial effect was tested on Salmonella strains, Streptococcus faecium , and spores and vegetative cells of Clostridium sporogenes . Cysteine-nitrosothiol showed a higher inhibitory effect than nitrite. Preliminary results on the effect of simultaneous use of nitrite and cysteine on Clostridium sporogenes spores were also presented.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference19 articles.

1. The Perigo effect in pork;Ashworth J.;J. Food Technol.,1972

2. Factors affecting the bacteriostatic action of sodium nitrite;Castellani A. G.;Appl. Microbiol.,1955

3. Isolation and identification of a hepatotoxic factor in herring meal produced from sodium nitrite preserved herring;Ender F.;Naturwissenschaften,1964

4. Effect of nitrite on the microbiological stability of canned Vienna sausages preserved by mild heat treatment or combinations of heat and irradiation;Farkas J.;Acta Alimentaria,1973

5. Fiddler W. E. G. Piotrowski J. W. Pensabene and A. E. Wasserman. 1972. Current observations on the occurrence and formation of N-nitrosamines p. 416-421. Proc. Meat Res. Workers Conf. Guelph.

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