Lack of Association between Toll-Like Receptor 2 Polymorphisms and Susceptibility to Severe Disease Caused by Staphylococcus aureus-Reference-Cited by-同舟云学术

Lack of Association between Toll-Like Receptor 2 Polymorphisms and Susceptibility to Severe Disease Caused by Staphylococcus aureus

Published:2004-11 Issue:6 Volume:11 Page:1194-1197
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Moore Catrin E.¹²³,Segal Shelley¹²³,Berendt Anthony R.¹²³,Hill Adrian V. S.¹²³,Day Nicholas P. J.¹²³

Affiliation:

1. Nuffield Department of Clinical Medicine, John Radcliffe Hospital

2. Bone Infection Unit, Nuffield Orthopaedic Centre NHS Trust, Oxford, United Kingdom

3. Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Abstract

ABSTRACT To investigate a putative link between genetically determined variations in Toll-like receptor 2 (TLR2) and the occurrence of severe Staphylococcus aureus infection, the functional Arg753Gln single-nucleotide polymorphism and the GT repeat microsatellite in the TLR2 gene were examined in a large case-control study. No associations with disease or mortality attributable to these features were found.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.11.6.1194-1197.2004

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