Effect of Hypoxia on the Pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa In Vitro and in Murine Experimental Models of Infection-Reference-Cited by-同舟云学术

Effect of Hypoxia on the Pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa In Vitro and in Murine Experimental Models of Infection

Published:2018-10 Issue:10 Volume:86 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Gil-Marqués María Luisa¹,Pachón-Ibáñez María Eugenía¹,Pachón Jerónimo¹,Smani Younes¹^ORCID

Affiliation:

1. Clinic Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain

Abstract

Hypoxia modulates bacterial virulence and the inflammation response through hypoxia-inducible factor 1α (HIF-1α). Here we study the influence of hypoxia on Acinetobacter baumannii and Pseudomonas aeruginosa infections.

Funder

Spanish Network for Research in Infectious Diseases

Ministerio de Educación Cultura y Deporte, Spain

Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, Spain

Ministerio de Economía y Competitividad (Miguel Servet tipo I), Spain, Subdirección General de Redes y Centros de Investigación Cooperativa

EC | European Regional Development Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00543-18