Proteomic Analysis of Phagocytosis in the Enteric Protozoan Parasite Entamoeba histolytica-Reference-Cited by-同舟云学术

Proteomic Analysis of Phagocytosis in the Enteric Protozoan Parasite Entamoeba histolytica

Published:2005-04 Issue:4 Volume:4 Page:827-831
ISSN:1535-9778
Container-title:Eukaryotic Cell
language:en
Short-container-title:Eukaryot Cell

Author:

Okada Mami¹²³,Huston Christopher D.⁴,Mann Barbara J.⁴,Petri William A.⁵,Kita Kiyoshi²,Nozaki Tomoyoshi¹³

Affiliation:

1. Department of Parasitology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511

2. Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033

3. Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, 2-20-5 Akebono-cho, Tachikawa, Tokyo 190-0012, Japan

4. Departments of Internal Medicine and Microbiology

5. Department of Medicine, Microbiology, and Pathology, University of Virginia Health System, Charlottesville, Virginia 22908-1340

Abstract

ABSTRACT Proteomic analysis of phagosomes isolated from Entamoeba histolytica by liquid chromatography and mass spectrometry identified 85 proteins involved in surface recognition, actin cytoskeleton rearrangement, vesicular trafficking, and degradation. Phagosome localization of representative proteins was verified by immunofluorescence assay. This study should provide a basis for molecular identification and characterization of phagosome biogenesis.

Publisher

American Society for Microbiology

Subject

Molecular Biology,General Medicine,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/EC.4.4.827-831.2005

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