Pellicle Biofilm Formation in <i>Burkholderia cenocepacia</i> J2315 is Epigenetically Regulated through WspH, a Hybrid Two-Component System Kinase-Response Regulator-Reference-Cited by-同舟云学术

Pellicle Biofilm Formation in Burkholderia cenocepacia J2315 is Epigenetically Regulated through WspH, a Hybrid Two-Component System Kinase-Response Regulator

Published:2022-05-17 Issue:5 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Sass Andrea¹,Vandenbussche Ian¹,Bellich Barbara²,Cescutti Paola²,Coenye Tom¹^ORCID

Affiliation:

1. Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

2. Department of Life Sciences, University of Trieste, Trieste, Italy

Abstract

Biofilms are surface-attached or suspended aggregates of cells, that are problematic in the context of bacterial infections, as they provide protection from antibiotic treatment. Burkholderia cenocepacia can colonize the lung of immunocompromised patients and forms biofilms that increase its recalcitrance to antibiotic treatment. Pellicles are biofilms which form at an air-liquid interface to take advantage of the higher oxygen concentrations in this environment.

Funder

UGent | Bijzonder Onderzoeksfonds UGent

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00017-22

Reference38 articles.

1. Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence

2. The Changing Microbial Epidemiology in Cystic Fibrosis

3. Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology

4. Social interactions in the Burkholderia cepacia complex: biofilms and quorum sensing

5. The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High‐Resolution Large‐Area Image Analysis Deciphers the Distribution of Salmonella Cells and ECM Components in Biofilms Formed on Charged PEDOT:PSS Surfaces;Advanced Science;2024-01-15

2. Metal Messengers: Communication in the Bacterial World through Transition-Metal-Sensing Two-Component Systems;Biochemistry;2023-08-04

3. Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection;Applied Microbiology and Biotechnology;2023-04-25

4. An optotracer-based antibiotic susceptibility test specifically targeting the biofilm lifestyle of Salmonella;Biofilm;2022-12