In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens-Reference-Cited by-同舟云学术

In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens

Published:2010-07 Issue:7 Volume:48 Page:2546-2549
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Tsakris Athanassios¹,Voulgari Evangelia¹,Poulou Aggeliki¹²,Kimouli Maria³,Pournaras Spyros⁴,Ranellou Kyriaki¹,Kosmopoulou Olga⁵,Petropoulou Dimitra³

Affiliation:

1. Department of Microbiology, Medical School, University of Athens, Athens

2. Department of Microbiology, Serres General Hospital, Serres

3. Department of Microbiology, Saint Panteleimon Hospital, Nicea

4. Department of Microbiology, Medical School, University of Thessaly, Larissa

5. Department of Internal Medicine, Saint Panteleimon Hospital, Nicea, Greece

Abstract

ABSTRACT Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla KPC-2 gene during the hospitalization.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00264-10

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