Clinical and Molecular Characteristics of Klebsiella pneumoniae Isolates Causing Bloodstream Infections in Japan: Occurrence of Hypervirulent Infections in Health Care-Reference-Cited by-同舟云学术

Clinical and Molecular Characteristics of Klebsiella pneumoniae Isolates Causing Bloodstream Infections in Japan: Occurrence of Hypervirulent Infections in Health Care

Published:2019-11 Issue:11 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Harada Sohei¹²³,Aoki Kotaro²,Yamamoto Shungo⁴,Ishii Yoshikazu²,Sekiya Noritaka⁵,Kurai Hanako⁶,Furukawa Keiichi⁷,Doi Asako⁸,Tochitani Kentaro⁴,Kubo Kenji⁹,Yamaguchi Yukihiro¹⁰,Narita Masashi¹¹¹²,Kamiyama Shinya¹³,Suzuki Jun¹⁴,Fukuchi Takahiko¹⁵,Gu Yoshiaki¹⁶,Okinaka Keiji¹⁷,Shiiki Soichi¹²,Hayakawa Kayoko¹⁸,Tachikawa Natsuo¹⁹,Kasahara Kei²⁰,Nakamura Tadahiro²¹,Yokota Kyoko²²²³,Komatsu Masanari²⁴,Takamiya Misaki²⁵,Tateda Kazuhiro²,Doi Yohei¹

Affiliation:

1. Department of Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

2. Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan

3. Department of Infectious Diseases, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan

4. Department of Infectious Diseases, Kyoto City Hospital, Kyoto, Japan

5. Department of Infection Prevention and Control, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan

6. Division of Infectious Diseases, Shizuoka Cancer Center Hospital, Nagaizumi, Shizuoka, Japan

7. Division of Infectious Diseases, St. Luke’s International Hospital, Tokyo, Japan

8. Department of Infectious Diseases, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan

9. Department of Infectious Diseases, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan

10. Department of infectious diseases, Kenwakai Otemachi Hospital, Kitakyushu, Fukuoka, Japan

11. Department of Medicine, Ohta Nishinouchi General Hospital, Koriyama, Fukushima, Japan

12. Division of Infectious Diseases, Okinawa Chubu Hospital, Uruma, Okinawa, Japan

13. Department of Clinical Laboratory Medicine and Infectious Diseases, Kurashiki Central Hospital, Kurashiki, Okayama, Japan

14. Division of General Internal Medicine, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan

15. Division of Infectious Disease Therapeutics, Department of Microbiology and Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan

16. Department of Infectious Diseases, Tohoku University Hospital, Sendai, Miyagi, Japan

17. Division of General Internal Medicine, National Cancer Center Hospital, Tokyo, Japan

18. Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan

19. Department of Infectious Diseases, Yokohama Municipal Citizen’s Hospital, Yokohama, Kanagawa, Japan

20. Center for Infectious Diseases, Nara Medical University, Kashihara, Nara, Japan

21. Department of Internal medicine, Japan Community Health care Organization Osaka Hospital, Osaka, Japan

22. Department of General Internal Medicine, Faculty of Medicine, Kagawa University, Takamatsu, Kagawa, Japan

23. Department of Infectious Diseases, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa, Japan

24. Division of General Medicine, Kagoshima Seikyo Hospital, Kagoshima, Japan

25. Department of infectious diseases, Hamamatsu Medical Center, Hamamatsu, Shizuoka, Japan

Abstract

Although hypervirulent Klebsiella pneumoniae (hvKp) has been associated with severe community-acquired infections that occur among relatively healthy individuals, information about hvKp infections in health care settings remains limited. Here, we systematically analyzed the clinical and molecular characteristics of K. pneumoniae isolates causing bloodstream infections in a cross-sectional study.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01206-19

Reference30 articles.

1. Primary Liver Abscess Due toKlebsiella pneumoniaein Taiwan

2. Genetic Determinants of Capsular Serotype K1 ofKlebsiella pneumoniaeCausing Primary Pyogenic Liver Abscess

3. Virulent Clones of Klebsiella pneumoniae: Identification and Evolutionary Scenario Based on Genomic and Phenotypic Characterization