Low-Level Viremia and Intracellular Expression of Hepatitis B Surface Antigen (HBsAg) in HBsAg Carriers with Concurrent Hepatitis C Virus Infection

Author:

Chu Chia-Ming1,Yeh Chau-Ting1,Liaw Yun-Fan1

Affiliation:

1. Liver Research Unit, Chang Gung Memorial Hospital and Medical College, Taipei, Taiwan

Abstract

ABSTRACT Assays of hepatitis B virus (HBV) replication and antigen expression in HBV surface antigen (HBsAg) carriers with concurrent hepatitis C or D virus (HCV or HDV) infection revealed that HCV and HDV can suppress HBV replication but that HCV also substantially suppresses HBV surface protein expression. HBsAg carriers with concurrent HCV infection thus have low-level viremia and intracellular HBsAg.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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