Role of FliC and FliD Flagellar Proteins of Clostridium difficile in Adherence and Gut Colonization-Reference-Cited by-同舟云学术

Role of FliC and FliD Flagellar Proteins of Clostridium difficile in Adherence and Gut Colonization

Published:2001-12 Issue:12 Volume:69 Page:7937-7940
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Tasteyre Albert¹,Barc Marie-Claude¹,Collignon Anne¹,Boureau Helene¹,Karjalainen Tuomo¹

Affiliation:

1. Département de Microbiologie, Faculté de Pharmacie, Université de Paris-Sud, 92296 Châtenay-Malabry Cedex, France

Abstract

ABSTRACT In vitro and in vivo adhesive properties of flagella and recombinant flagellin FliC and flagellar cap FliD proteins of Clostridium difficile were analyzed. FliC, FliD, and crude flagella adhered in vitro to axenic mouse cecal mucus. Radiolabeled cultured cells bound to a high degree to FliD and weakly to flagella deposited on a membrane. The tissue association in the mouse cecum of a nonflagellated strain was 10-fold lower than that of a flagellated strain belonging to the same serogroup, confirming the role of flagella in adherence.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.69.12.7937-7940.2001

Reference41 articles.

1. The Pseudomonas aeruginosa Flagellar Cap Protein, FliD, Is Responsible for Mucin Adhesion

2. Investigation of a nosocomial outbreak of Clostridium difficile-associated diarrhoea among AIDS patients by random amplified polymorphic DNA (RAPD) assay;Barbut F.;J. Hosp. Infect.,1994

3. Antibiotic associated pseudomembranous colitis due to toxin producing clostridia;Bartlett J. G.;N. Engl. J. Med.,1978

4. Flagella in prokaryotes and lower eukaryotes;Blair D. F.;Curr. Opin. Genet. Dev.,1992

5. Role of bacterial metabolism and physiology in the pathogenesis of Clostridium difficile disease;Bongaerts G. P.;Microb. Pathog.,1997

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