Author:
Aydanian Antonina,Tang Li,Morris J. Glenn,Johnson Judith A.,Stine O. Colin
Abstract
ABSTRACTO-antigen biosynthetic (wbf) regions forVibrio choleraeserogroups O5, O8, and O108 were isolated and sequenced. Sequences were compared to those of other publishedV. choleraeO-antigen regions. Thesewbfregions showed a high degree of heterogeneity both in gene content and in gene order. Genes identified frequently showed greater similarities to polysaccharide biosynthesis genes from species other thanV. cholerae. Our results demonstrate the plasticity of O-antigen genes inV. cholerae, the diversity of the genetic pool from which they are drawn, and the likelihood that new pandemic serogroups will emerge.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
29 articles.
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