Francisella tularensis Exploits AMPK Activation to Harvest Host-Derived Nutrients Liberated from Host Lipolysis-Reference-Cited by-同舟云学术

Francisella tularensis Exploits AMPK Activation to Harvest Host-Derived Nutrients Liberated from Host Lipolysis

Published:2022-08-18 Issue:8 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Dominguez Sedelia R.¹²^ORCID,Whiles Shannon¹,Deobald Kelly N.¹,Kawula Thomas¹²^ORCID

Affiliation:

1. Paul G. Allen School for Global Health, Washington State University, Pullman, Washington, USA

2. School of Molecular Biosciences, Washington State University, Pullman, Washington, USA

Abstract

Francisella tularensis is a zoonotic, facultative intracellular bacterial pathogen that replicates in a variety of cell types during infection. Following entry into the cell and phagosome escape, the bacterium replicates rapidly in the cytoplasm. F. tularensis intracellular growth depends on the availability of metabolizable essential nutrients to support replication.

Funder

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00155-22

Reference55 articles.

1. A review on host–pathogen interactions: classification and prediction

2. Microbial quest for foodin vivo: ‘Nutritional virulence’ as an emerging paradigm

3. Nutrition and Bipartite Metabolism of Intracellular Pathogens

4. Manipulation of Host Cell Organelles by Intracellular Pathogens

5. Francisella tularensisas a potential agent of bioterrorism?

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