Correlation of Trichosporon asahii Genotypes with Anatomical Sites and Antifungal Susceptibility Profiles: Data Analyses from 284 Isolates Collected in the Last 22 Years across 24 Medical Centers-Reference-Cited by-同舟云学术

Correlation of Trichosporon asahii Genotypes with Anatomical Sites and Antifungal Susceptibility Profiles: Data Analyses from 284 Isolates Collected in the Last 22 Years across 24 Medical Centers

Published:2021-02-17 Issue:3 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Francisco Elaine Cristina¹,de Almeida Junior João N.²,Queiroz-Telles Flávio³^ORCID,Aquino Valério Rodrigues⁴,Mendes Ana Verena A.⁵,de Oliveira Silva Marcio⁵,Castro Paulo de Tarso O. e⁶,Guimarães Thais⁷^ORCID,Ponzio Vinicius⁸,Hahn Rosane C.⁹,Chaves Guilherme M.¹⁰,Colombo Arnaldo L.¹^ORCID

Affiliation:

1. Laboratório Especial de Micologia, Division of Infectious Diseases, Universidade Federal de São Paulo, São Paulo, Brazil

2. Hospital das Clínicas da FMUSP, São Paulo, Brazil

3. Universidade Federal do Paraná, Curitiba, Paraná, Brazil

4. Hospital das Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

5. Hospital São Rafael de Salvador, Salvador, Bahia, Brazil

6. Hospital de Câncer de Barretos, Barretos, São Paulo, Brazil

7. Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil

8. Hospital Nove de Julho, São Paulo, Brazil

9. Universidade Federal de Mato Grosso, Cuiabá, Brazil

10. Universidade Federal do Rio Grande do Norte, Natal, Brazil

Abstract

Trichosporon asahii is an opportunistic fungal pathogen that can cause severe infections with high mortality rates. Azole derivatives are the best-targeted therapy for T. asahii invasive infections, but azole-resistant isolates have been reported.

Funder

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01104-20

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