VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes-Reference-Cited by-同舟云学术

VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes

Published:2022-08-30 Issue:4 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Lu Shiou-Ling¹,Omori Hiroko²,Zhou Yi¹,Lin Yee-Shin³⁴,Liu Ching-Chuan⁴⁵,Wu Jiunn-Jong⁶,Noda Takeshi¹⁷^ORCID

Affiliation:

1. Center for Frontier Oral Science, Graduate School of Dentistry, Osaka University, Osaka, Japan

2. Research Institute for Microbial Disease, Osaka University, Osaka, Japan

3. Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

4. Center of Infectious Disease and Signaling Research, College of Medicine, National Cheng Kung University, Tainan, Taiwan

5. Department of Pediatrics, College of Medicine, National Cheng Kung University, Tainan, Taiwan

6. Department of Biotechnology and Laboratory Science in Medicine, College of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei, Taiwan

7. Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

Abstract

Sepsis caused by Streptococcus pyogenes is a life-threatening condition. Blood vessel endothelial cells should serve as a barrier to infection, although we recently reported that endothelial cells allow intracellular GAS proliferation due to defective xenophagy.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01233-22

Reference58 articles.

1. Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

2. Intracellular Invasion by Streptococcus pyogenes : Invasins, Host Receptors, and Relevance to Human Disease

3. Update on group A streptococcal vaccine development

4. Role of M3 protein in the adherence and internalization of an invasiveStreptococcus pyogenesstrain by epithelial cells

5. Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Profiling of serum factors associated with Staphylococcus aureus skin and soft tissue infections as a foundation for biomarker identification;Frontiers in Immunology;2023-11-20

2. Application and value of hydrogen sulfide modulated autophagy in sepsis;International Immunopharmacology;2023-09

3. Novel evidence on sepsis-inducing pathogens: from laboratory to bedside;Frontiers in Microbiology;2023-06-23

4. VEGF (vascular endothelial growth factor) provides antimicrobial effects via autophagy and lysosomal empowerment in endothelial cells;Autophagy Reports;2022-10-24