Author:
Chiou Jiachi,Li Ruichao,Chen Sheng
Abstract
ABSTRACTVibrio parahaemolyticusis commonly resistant to ampicillin, yet the mechanisms underlying this phenomenon are not clear. In this study, a novel class A carbenicillin-hydrolyzing β-lactamase (CARB) family of β-lactamases,blaCARB-17, was identified and found to be responsible for the intrinsic penicillin resistance inV. parahaemolyticus. Importantly,blaCARB-17-like genes were present in all 293V. parahaemolyticusgenome sequences available in GenBank and detectable in all 91V. parahaemolyticusfood isolates, further confirming the intrinsic nature of this gene.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference19 articles.
1. Clinical aspects of acute intestinal infection caused by Vibrio parahaemolyticus;Vrach Delo,1986
2. Detection of numerous verotoxigenic E. coli serotypes, with multiple antibiotic resistance from cattle faeces and soil;Vet Microbiol,2009
3. Clinical manifestation and prognostic factors of non-cholerae Vibrio infections;Eur J Clin Microbiol Infect Dis,2011
4. Draft genome sequence of Vibrio parahaemolyticus V110, isolated from shrimp in Hong Kong;Genome Announc,2013
5. Performance standards for antimicrobial susceptibility testing;Clinical and Laboratory Standards Institute,2013
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