Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

Author:

Williams Eloise123ORCID,Zhang Bowen12,Chow Eric P. F.345ORCID,Chea Socheata2,Phillips Tiffany R.34,Maddaford Kate3,Krysiak Marcelina2,Nong Yi6ORCID,Stefanatos Helen2,Pasricha Shivani2ORCID,Fairley Christopher K.34,Wiliamson Deborah A.27ORCID

Affiliation:

1. Department of Microbiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia

2. Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute, Melbourne, Victoria, Australia

3. Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia

4. Central Clinical School, Monash University, Melbourne, Victoria, Australia

5. Melbourne School of Population and Global Health, The University of Melbourne, Carlton, Victoria, Australia

6. Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute, Melbourne, Victoria, Australia

7. Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute, Melbourne, Victoria, Australia

Abstract

Improved treatment and prevention strategies, such as antimicrobial mouthwashes, may be important for addressing the public health threat of antimicrobial-resistant Neisseria gonorrhoeae . Here, we describe the activity of seven common antibacterial mouthwashes and antiseptics against N. gonorrhoeae isolates, incorporating the use of a human saliva test matrix.

Funder

Department of Health | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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