Evaluation of the hemagglutination treponemal test for syphilis

Author:

Moyer N P,Hudson J D,Hausler W J

Abstract

The sensitivity and specificity of the hemagglutination treponemal test for syphilis (HATTS) was compared with the fluorescent treponemal antibody-absorption test (FTA-ABS) with 491 sera. Medical histories were obtained for 153 patients with seroreactivity in either treponemal test. Overall correlation with patient history was 96.7% for the FTA-ABS and 93.9% for the HATTS. False-negative HATTS occurred in primary, late-latent (greater than 2 years), and treated syphilis. The reproducibility of the HATTS and FTA-ABS is equivalent. HATTS is an acceptable treponemal confirmatory test for syphilis, but the FTA-ABS should be used to resolve diagnostic discrepancies.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference7 articles.

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1. Sensitivity and Specificity of Treponemal-specific Tests for the Diagnosis of Syphilis;Clinical Infectious Diseases;2020-06-24

2. Nosocomial Transmission of Syphilis During Haemodialysis in a Developing Country;Scandinavian Journal of Infectious Diseases;2002-01

3. The Office Microbiology Laboratory;Urologic Clinics of North America;1986-11

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