Comparison of sputum counterimmunoelectrophoresis and culture in diagnosis of pneumococcal pneumonia

Author:

Downes B A,Ellner P D

Abstract

The diagnostic value of counterimmunoelectrophoresis performed on sputum was compared with that of sputum culture. The detection of pneumococcal polysaccharide in sputum showed a better correlation with the presence of pneumococcal pneumonia than the recovery of pneumococci by culture. The authors conclude that sputum counterimmunoelectrophoresis can provide diagnostic guidance to physicians awaiting the results of sputum culture and aid in the interpretation of cultural findings.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference20 articles.

1. Austrian R. and I. L. Bennett Jr. 1974. Pneumococcal infection p. In M. M. Wintrobe et al. (ed.) Harrison's principles of internal medicine 7th ed. McGraw-Hill Book Co. New York.

2. The nonvalue of sputum culture in the diagnosis of pneumococcal pneumonia;Barrett-Connor E.;A. Rev. Respir. Dis.,1971

3. Diagnosis of pneumonia by counterimmunoelectrophoresis of respiratory secretions;Congeni B. L.;Am. J. Dis. Child.,1978

4. Pneumococcal pneumonia: capsular polysaccharide antigenemia and antibody responses;Coonrod J. D.;Ann. Int. Med.,1976

5. Detection of type-specific pneumococcal antigens by counterimmunoelectrophoresis. I. Methodology and immunologic properties of pneumococcal antigens;Coonrod J. D.;J. Lab. Clin. Med.,1973

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