Evaluation of a commercial monoclonal antibody for detection of adenovirus antigen

Author:

August M J1,Warford A L1

Affiliation:

1. SmithKline Bio-Science Laboratories, Van Nuys, California 91405.

Abstract

The Adenoclone monoclonal antibody for detection of adenovirus antigen was evaluated by enzyme immunoassay and a 72-h indirect fluorescent-antibody test in shell vials and compared with standard culture. The sensitivity and specificity of the Adenoclone test were both 100% with 114 cell culture isolates. With 310 direct clinical specimens, the Adenoclone enzyme immunoassay sensitivity varied from 14.3 to 66.6%, but the Adenoclone indirect fluorescent-antibody test sensitivity was 86.7%, with 100% specificity.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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2. Adenovirus;Microbiology Spectrum;2016-08-12

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4. Adenoviruses;Manual of Clinical Microbiology;2015-05-26

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