Cutibacterium acnes Central Nervous System Catheter Infection Induces Long-Term Changes in the Cerebrospinal Fluid Proteome-Reference-Cited by-同舟云学术

Cutibacterium acnes Central Nervous System Catheter Infection Induces Long-Term Changes in the Cerebrospinal Fluid Proteome

Published:2021-03-17 Issue:4 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Beaver Matthew¹,Lagundzin Dragana²,Thapa Ishwor³,Lee Junghyae⁴,Ali Hesham³,Kielian Tammy⁵^ORCID,Skar Gwenn L.¹^ORCID

Affiliation:

1. Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska, USA

2. Mass Spectrometry and Proteomics Core Facility, University of Nebraska Medical Center, Omaha, Nebraska, USA

3. College of Information Science and Technology, University of Nebraska Omaha, Omaha, Nebraska, USA

4. Department of Biostatistics, University of Nebraska Medical Center, Omaha, Nebraska, USA

5. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA

Abstract

Cutibacterium acnes is the third most common cause of cerebrospinal fluid (CSF) shunt infection and is likely underdiagnosed due to the difficulty in culturing this pathogen. Shunt infections lead to grave neurologic morbidity for patients especially when there is a delay in diagnosis.

Funder

Legeschulte & Wiese Fund at the University of Nebraska Medical Center

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00531-20

Reference51 articles.

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