Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages-Reference-Cited by-同舟云学术

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages

Published:2018-10 Issue:10 Volume:86 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Clemente Tatiana M.¹,Mulye Minal¹,Justis Anna V.¹,Nallandhighal Srinivas²,Tran Tuan M.²,Gilk Stacey D.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA

2. Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA

Abstract

Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole membrane into the host cytoplasm, where they manipulate a variety of cell processes.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00532-18

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