The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model-Reference-Cited by-同舟云学术

The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Hiramatsu Yukihiro¹^ORCID,Suzuki Koichiro¹²,Nishida Takashi¹,Onoda Naoki¹,Satoh Takashi³,Akira Shizuo³⁴,Ikawa Masahito⁵⁴,Ikeda Hiroko⁶,Kamei Junzo⁷,Derouiche Sandra⁸⁹,Tominaga Makoto⁸⁹,Horiguchi Yasuhiko¹⁴^ORCID

Affiliation:

1. Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

2. The Research Foundation for Microbial Diseases of Osaka University (BIKEN), Suita, Osaka, Japan

3. Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

4. Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, Japan

5. Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

6. Department of Pathophysiology and Therapeutics, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan

7. Juntendo Advanced Research Institute for Health Science, Juntendo University, Tokyo, Japan

8. Division of Cell Signaling, National Institute for Physiological Sciences, Okazaki, Aichi, Japan

9. Thermal Biology Group, Exploratory Research Center on Life and Living Systems (ExCELLS), Okazaki, Aichi, Japan

Abstract

The Gram-negative bacteriumBordetella pertussiscauses a respiratory disease called whooping cough, or pertussis. This disease is characterized by paroxysmal coughing, the mechanism of which has not been intensively studied because of a lack of versatile animal models that reproduce the cough.

Funder

MEXT | Japan Society for the Promotion of Science

MEXT |Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03197-21

Reference103 articles.

1. Pertussis Across the Globe

2. Waning and aging of cellular immunity toB. pertussis