Reliability of two new test kits for rapid diagnosis of respiratory syncytial virus infection

Author:

Rothbarth P H1,Hermus M C1,Schrijnemakers P1

Affiliation:

1. Department of Virology, University Hospital Rotterdam, The Netherlands.

Abstract

Two new rapid enzyme immunoassays (EIAs) for detecting respiratory syncytial virus (RSV), Directigen (Becton Dickinson Microbiology Systems) and TestPack (Abbott Diagnostics) were compared with virus isolation and direct immunofluorescence by using fresh specimens. The sensitivities of both EIAs were low (72 to 73%), but when initial specimens were used, TestPack had a high sensitivity (92%) in contrast to that of Directigen (76%). Because of its high sensitivity and specificity, TestPack can be used for diagnosis of RSV in acute disease.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference15 articles.

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