Measles Virus Induces Functional TRAIL Production by Human Dendritic Cells-Reference-Cited by-同舟云学术

Measles Virus Induces Functional TRAIL Production by Human Dendritic Cells

Published:2000-01 Issue:1 Volume:74 Page:556-559
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Vidalain Pierre-Olivier¹,Azocar Olga¹,Lamouille Barbara¹,Astier Anne¹,Rabourdin-Combe Chantal¹,Servet-Delprat Christine¹

Affiliation:

1. Laboratoire d'Immunobiologie Fondamentale et Clinique, INSERM U503, ENS de Lyon, 69364 Lyon Cedex 07, France

Abstract

ABSTRACT Measles virus infection induces a profound immunosuppression that can lead to serious secondary infections. Here we demonstrate that measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mRNA and protein expression in human monocyte-derived dendritic cells. Moreover, measles virus-infected dendritic cells are shown to be cytotoxic via the TRAIL pathway.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.74.1.556-559.2000

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