Detection and Quantification of CD4 + T Cells with Specificity for a New Major Histocompatibility Complex Class II-Restricted Influenza A Virus Matrix Protein Epitope in Peripheral Blood of Influenza Patients-Reference-Cited by-同舟云学术

Detection and Quantification of CD4 + T Cells with Specificity for a New Major Histocompatibility Complex Class II-Restricted Influenza A Virus Matrix Protein Epitope in Peripheral Blood of Influenza Patients

Published:2000-09-15 Issue:18 Volume:74 Page:8740-8743
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Linnemann Thomas¹,Jung Günther²,Walden Peter¹

Affiliation:

1. Department of Dermatology and Allergy, Charité, Medical School of the Humboldt University, D-10089 Berlin,1 and

2. Department of Organic Chemistry, University of Tübingen, D-72074 Tübingen,2 Germany

Abstract

ABSTRACT FVFTLTVPS was identified as the core sequence of a new major histocompatibility complex class II-restricted T-cell epitope of influenza virus matrix protein. Epitope-specific CD4 + T cells were detected in the peripheral blood of patients with frequencies of up to 0.94%, depending on the number of additional terminal amino acids.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.74.18.8740-8743.2000

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