Identification of a Bovine Coronavirus Packaging Signal-Reference-Cited by-同舟云学术

Identification of a Bovine Coronavirus Packaging Signal

Published:2000-01 Issue:1 Volume:74 Page:580-583
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Cologna Raymond¹,Hogue Brenda G.¹²

Affiliation:

1. Division of Molecular Virology1 and

2. Department of Microbiology and Immunology,2 Baylor College of Medicine, Houston, Texas 77030

Abstract

ABSTRACT A region of the bovine coronavirus (BCV) genome that functions as a packaging signal has been cloned. The 291-nucleotide clone shares 72% homology with the region of mouse hepatitis coronavirus (MHV) gene 1b that contains the packaging signal. RNA transcripts were packaged into both BCV and MHV virions when the cloned region was appended to a noncoronavirus RNA. This is the first identification of a BCV packaging signal. The data demonstrate that the BCV genome contains a sequence that is conserved at both the sequence and functional levels, thus broadening our insight into coronavirus packaging.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.74.1.580-583.2000

Reference32 articles.

1. Deduced sequence of the bovine coronavirus spike protein and identification of the internal proteolytic cleavage site;Abraham S.;Virology,1990

2. Sequence and expression analysis of potential nonstructural proteins of 4.9, 4.8, 12.7, and 9.5 kDa encoded between the spike and membrane protein genes of the bovine coronavirus;Abraham S.;Virology,1990

3. Interactions between coronavirus nucleocapsid protein and viral RNAs: implications for viral transcription

4. A subgenomic mRNA transcript of the coronavirus mouse hepatitis virus strain A59 defective interfering (DI) RNA is packaged when it contains the DI packaging signal

5. The primary structure and expression of the 2 open reading frame of the polymerase gene of the coronavirus MHV-A59—a highly conserved polymerase is expressed by an efficient ribosomal frame-shifting mechanism;Bredenbeek B. J.;Nucleic Acids Res.,1990

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Managing viral challenges in dairy calves: strategies for controlling viral infections;Cogent Food & Agriculture;2024-05-09

2. The coronavirus recombination pathway;Cell Host & Microbe;2023-06

3. Assembly of Coronaviruses and CoV-Like-Particles;Physical Virology;2023

4. A synthetic defective interfering SARS-CoV-2;PeerJ;2021-07-01

5. The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA;Nature Communications;2021-03-29