A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin-Reference-Cited by-同舟云学术

A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin

Published:2000-04 Issue:4 Volume:44 Page:1089-1092
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Zhanel George G.¹²³⁴,Karlowsky James A.¹²⁴,Harding Godfrey K. M.¹⁵,Carrie Anita²,Mazzulli Tony⁶⁷,Low Donald E.⁶⁷,Hoban Daryl J.¹⁴,

Affiliation:

1. Department of Medical Microbiology, Faculty of Medicine,1 and

2. Faculty of Pharmacy,2 University of Manitoba, and

3. Departments of Medicine3 and

4. Clinical Microbiology,4 Health Sciences Centre, and

5. Department of Microbiology, St. Boniface General Hospital,5 Winnipeg, Manitoba, and

6. Department of Microbiology, Mount Sinai and Princess Margaret Hospitals, University of Toronto,6 and

7. Med-Chem Health Care, Ltd.,7 Toronto, Ontario, Canada

Abstract

ABSTRACT Ampicillin, trimethoprim-sulfamethoxazole, mecillinam, nitrofurantoin, and ciprofloxacin mean resistance rates for 2,000 urinary tract isolates collected from outpatients across Canada in 1998 were 41.1, 19.2, 14.7, 5.0, and 1.8%, respectively. For Escherichia coli isolates alone ( n = 1,681) comparable rates were 41.0, 18.9, 7.4, 0.1, and 1.2%, respectively. The majority of E. coli isolates resistant to ampicillin, trimethoprim-sulfamethoxazole, or ciprofloxacin were susceptible (MIC, <16 μg/ml) to mecillinam.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.4.1089-1092.2000

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