Mechanism of Tolerance to the Lignin-Derived Inhibitor p -Benzoquinone and Metabolic Modification of Biorefinery Fermentation Strains-Reference-Cited by-同舟云学术

Mechanism of Tolerance to the Lignin-Derived Inhibitor p -Benzoquinone and Metabolic Modification of Biorefinery Fermentation Strains

Published:2019-11-15 Issue:22 Volume:85 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Yan Zhao¹,Gao Xiaochuang¹,Gao Qiuqiang¹,Bao Jie¹^ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Abstract

This study advances our understanding of BQ inhibition behavior and the mechanism of microbial tolerance to this inhibitor and identifies the key genes responsible for BQ detoxification. The insights here into BQ toxicity and tolerance provide the basis for future synthetic biology to engineer industrial fermentation strains with enhanced BQ tolerance.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01443-19

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