Emergence, Evolution, and Pathogenicity of Influenza A(H7N4) Virus in Shorebirds in China-Reference-Cited by-同舟云学术

Emergence, Evolution, and Pathogenicity of Influenza A(H7N4) Virus in Shorebirds in China

Published:2022-02-09 Issue:3 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chai Hongliang¹^ORCID,Li Xiang¹,Li Minghui²,Lv Xinru¹,Yu Wentao²,Li Yi¹,Sun Jing¹,Li Yulei²,Sun Heting³,Tian Jingman²,Xu Yu³,Bai Xiaoli²,Peng Peng³,Xie Linhong³,Qin Siyuan³,An Qing¹,Zhang Fengjiang⁴,Zhang Hailong⁴,Du Jiang⁵,Yang Siyuan¹⁶,Hou Zhijun¹,Zeng Xiangwei¹,Wang Yulong¹,Richt Juergen A.⁷,Wang Yajun¹,Li Yanbing²^ORCID,Ma Jianzhang¹

Affiliation:

1. College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China

2. Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

3. General Station for Surveillance of Wildlife Disease & Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China

4. Liaoning Wildlife Protection and Epidemic Disease Monitoring Center, Dalian, China

5. Forestry and Grassland Affairs Service Center, Donggang Forestry and Grassland Administration, Donggang, China

6. Heilongjiang Vocational College for Nationalities, Harbin, China

7. Diagnostic Medicine/Pathobiology, Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD), College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA

Abstract

The H7 subtype avian influenza viruses, such as H7N2, H7N3, H7N4, H7N7, and H7N9, were documented as being capable of infecting humans, and the H7 subtype low pathogenicity avian influenza viruses are capable of mutating into highly pathogenic avian influenza; therefore, they pose a serious threat to public health. Here, we investigated the evolutionary history, molecular characteristics, and pathogenicity of shorebird-origin influenza A(H7N4) viruses, showing a similar evolutionary trajectory with Jiangsu human A(H7N4) viruses in HA and NA genes.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01717-21

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